It Turns Out That Lowering Uric Acid Is So Easy, This Natural Food That You Often Eat Can
In recent years, scientific research has found that black plum juice concentrate (PFC) rich in polysaccharides has a significant effect on reducing high uric acid and improving chronic kidney disease.
1. High uric acid and chronic kidney disease: inseparable
Uric acid is the final product of purine metabolism in the human body and is mainly excreted through the kidneys and intestines. However, when uric acid is produced too much or is not excreted smoothly, it will lead to increased uric acid concentration in the blood, forming hyperuricemia. High uric acid not only causes gout, leading to redness, swelling, heat and pain in the joints, but also damages the kidneys and causes chronic kidney disease. Chronic kidney disease is a disease characterized by a gradual decline in renal function, and high uric acid is one of its important risk factors.
2. Black plum: an ancient medicinal and edible product
Black plum, a fruit widely cultivated in my country, Japan, South Korea and other places, is not only colorful and pleasant in aroma, but also has high medicinal and nutritional value. Wumei's fruits, leaves and seeds are widely used in traditional medicine. For example, Wumei fruit extract can reduce serum uric acid concentration in hyperuricemia mice, and Wumei leaf extract can reduce blood sugar levels in diabetic mice. Today we will focus on Wumei juice concentrate (PFC) rich in polysaccharides.
3. Plum juice concentrate: a new hope for lowering uric acid
Polysaccharide-rich plum juice concentrate (PFC) is a product made by boiling plum juice for a long time and repeatedly concentrating it. It is rich in polysaccharides, which have many benefits for human health. Scientific studies in recent years have found that PFC has a significant effect on reducing high uric acid and improving chronic kidney disease.
In one study, scientists divided mice into four groups and fed them different feeds and PFC. The results showed that the mice given PFC had a significant increase in uric acid excretion and a significant decrease in serum uric acid concentration. This effect may be achieved by regulating uric acid transporters in the kidneys and intestines. Uric acid transporters are important proteins responsible for uric acid excretion. PFC can increase the expression of transporters that are beneficial to uric acid excretion, while reducing the expression of transporters that are not conducive to uric acid excretion.
4. How does black plumjuice concentrate lower uric acid?
Regulates uric acid transporter expression
Uric acid is mainly excreted from the body through the kidneys and intestines. In the kidneys, uric acid transporters are responsible for excreting uric acid from the blood into the urine. PFC can increase the expression of transporters in the kidneys that are conducive to uric acid excretion (such as ABCG2, OAT1, OCTN2), while reducing the expression of transporters that are not conducive to uric acid excretion (such as GLUT9, URAT1). In this way, more uric acid can be excreted from the body, thereby reducing serum uric acid concentration.
Improves gut microbiome
The intestinal microbiota has an important impact on human health. Recent studies have found that intestinal microbial imbalance is closely related to the occurrence and development of diseases such as chronic kidney disease. PFC can significantly improve the structure and function of the intestinal microbiota. It increases the number and types of beneficial bacteria and reduces the abundance of harmful bacteria. These beneficial bacteria can produce beneficial metabolites such as short-chain fatty acids, which further promote the excretion of uric acid.
5. How to take black plumjuice concentrate?
Although black plum juice concentrate has many health benefits, it is not suitable for everyone to consume directly. Generally speaking, for patients with high uric acid, chronic kidney disease, etc., it is relatively safe to consume it in moderation under the guidance of a doctor. In addition, there are also some health products or functional foods made from black plum juice concentrate on the market for consumers to choose from. When purchasing, it is recommended to choose a regular brand, check the product ingredients and efficacy description, and follow the recommendations in the product manual for consumption.