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Have you heard of dihydromyricetin (DHM)?
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Have you heard of dihydromyricetin (DHM)?

2025-09-03

What is Kenponashi ExtractKenponashi is a deciduous tree of the Rhamnaceae family, native to East Asia, from Hokkaido to Kyushu, China, and the Korean Peninsula. It has long been used in traditional Chinese medicine and folk remedies, with its fruit and bark, in particular, containing numerous compounds that support liver function. It is also famous as a medicinal herb, primarily believed to be effective against alcohol poisoning. Its decoction and extract have long been used as herbal medicine and tea. While Kenponashi benefits the liver, it may help restore liver function in alcoholics. However, it is not effective in cases where liver function has been impaired by stress or overwork. Its high content of ampelopsin, which breaks down alcohol, makes it effective in relieving hangovers and also in treating alcoholic hepatitis and fatty liver. Its main component is dihydromyricetin (DHM). For this reason, it has long been known as a "friend of alcoholics" and has recently gained attention as an ingredient in health foods and supplements. A study aimed to investigate the pharmacological effects of dihydromyricetin  (DHM). The results showed that DHM has very little toxicity.

Expected Benefits

Liver care for alcoholics: Supports the recovery of liver function weakened by alcohol;Relieves morning fatigue and hangovers, allowing you to wake up feeling refreshed;May also help prevent fatty liver and alcoholic hepatitis;

Regulates gastrointestinal function: Aids digestion and prevents stomach upset; Improves bowel movements and promotes the excretion of waste products from the body;

Potential health benefits: Relieves fatigue and joint stiffness;Helps stabilize blood sugar and blood pressure;Supports youthfulness through antioxidant effects;Helps treat unpleasant bad breath and alcohol odor;

Antioxidant Effects: 98% pure dihydromyricetin  significantly inhibits the production of malondialdehyde (MDA) in rat myocardial, liver, and brain tissue homogenates. Furthermore, increasing the dihydromyricetin concentration strengthens the inhibitory effect on MDA production, and dihydromyricetin with a 99% content reduces DPPH free radicals in experimental systems. Dihydromyricetin can significantly inhibit the production of MDA in fats and oils. The antioxidant effect becomes stronger as the purity of dihydromyricetin increases (60% to 90%), and it has strong antioxidant properties in both animal and vegetable oils.

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Antibacterial Effects: Pharmacological experiments have shown that dihydromyricetin  inhibits Bacillus subtilis, Staphylococcus aureus, Salmonella enterica, Escherichia coli, Streptococcus aerogenes, brewer's yeast, Penicillium niger, Aspergillus flavus, hair mold, and Rhizopus, and it is said to have clear effects on Gram-positive and Gram-negative bacteria and bacilli.

Anti-tumor Effects: Recent research into the efficacy of anti-tumor drugs has found that one of its active ingredients, the small molecule compound ampellopsin, has strong anti-cancer effects. In vitro research into its anti-tumor effects has shown that this compound inhibits the growth of tumor blood vessels and regulates and strengthens cellular immune functions, thereby enhancing the effectiveness of tumor treatment and improving patients' vital signs. It is said that it has clearly demonstrated antitumor effects in tumor model experiments on leukemia and nasopharyngeal carcinoma.

Product Drawbacks: Poor effectiveness: Noticeable effects take a long time to show; Unpleasant taste: Bitter and difficult to swallow; Unpleasant odor: Smoky and unpleasant odors develop after long-term storage.

Our Product Features: High dihydromyricetin  content: Up to 20%; High solubility: Disperses evenly in cold water at 50 mg/ml; High bioavailability: Bioavailability increased by 7.5 times.

Alcohol Metabolism Clinical Trial Data: Measurement Instrument: Breath Alcoholometer; Testing Method: 50mL 53% alcohol (Day 1); 2g Hovenia Dulcis Instant Powder + 50mL 53% alcohol (Day 2). Alcohol levels were recorded at each time point.

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Conclusions: 1. After taking dihydromyricetin  Powder, the dihydromyricetin  group experienced a 20.73%-35.29% increase in hangover recovery compared to the control group at each time point. 2. The dihydromyricetin group experienced a half-hour improvement in hangover recovery.

Recommended for:People who have tried liver-related products but stopped because they were ineffective; People who often go out drinking after work;People who enjoy alcohol and drink frequently。