Ginkgo biloba extract may bring new hope for the treatment of neurodegenerative disease

Ginkgo biloba leaf extract, as a natural ingredient widely used in the fields of medicine and health products, has always been highly regarded for its pharmacological activity. Recently, significant progress has been made in the study of the core components of Ginkgo biloba extract, particularly in its potential for the treatment of neurodegenerative diseases.
Ginkgo biloba is one of the oldest surviving tree species, and its fan-shaped leaf extract is rich in flavonoids and terpenoids, such as ginkgolide B. Previous studies have shown that bilobalide may have various potential effects such as brain protection, anti-inflammatory, and antiepileptic effects.

However, the complex chemical structure and instability of bilobalide make it difficult to directly develop into medicine.

Molecular editing technology breaks through the bottleneck of traditional Chinese medicine

According to reports, a research team from the School of Pharmacy at a well-known university's medical school has successfully developed a new "chemical molecular editing technology". This technology can finely modify the molecular structure of bilobalide, thereby developing "bilobalide derivatives" with higher pharmaceutical value.
The research team pointed out that this breakthrough provides new hope and direction for drug development for neurodegenerative diseases such as Alzheimer's disease. Through chemical modification, the complex structure and easy decomposition of natural compounds can be overcome, further exploring and utilizing the potential therapeutic effects of Ginkgo biloba leaf extract.

Continuous research on the clinical application of Ginkgo biloba leaf extract

In addition to making progress in basic research, research on the clinical application of Ginkgo biloba extract has never stopped. Multiple clinical expert consensus and research reports indicate that Ginkgo biloba extract preparations have application value in the following areas:
Cerebrovascular disease: Ginkgo biloba extract injection is recommended for the treatment of acute ischemic stroke (such as cerebral infarction), which can help improve neurological deficits.

Cognitive impairment and dementia: Clinical evidence shows that Ginkgo biloba extract is beneficial for the clinical prevention and treatment of mild cognitive impairment and dementia, whether used alone or in combination with other drugs, and can improve cognitive impairment.
Cardiovascular disease: Relevant studies support its application in the treatment of coronary heart disease, which can help improve myocardial function and reduce levels of inflammatory factors.、

Regulation and quality control remain the focus

It is worth noting that due to the complexity of the plant extract market, regulatory and quality control issues remain a major challenge for the Ginkgo biloba extract industry. Previously, there were reports exposing that some companies were falsifying their extraction processes and changing their extraction methods without authorization, which affected the quality and safety of their products.

The regulatory authorities have conducted strict reviews and regulations, requiring pharmaceutical companies to use plant extracts with approval numbers for active pharmaceutical ingredients, in order to regulate the market and ensure public drug safety.

In summary, Ginkgo biloba extract is currently in a critical period of deepening basic research and expanding clinical applications. With the advancement of science and technology and the strengthening of regulation, this ancient natural medicine is expected to play a more important role in fields such as neurodegenerative diseases in the future.