Do you know PQQ of health food ingredients ？

What is pyrroloquinoline quinone?

PQQ (pyroloquinoline quinone) is a component that is naturally contained in our bodies and in the foods and drinks we consume. It is found in high concentrations in breast milk, which is essential for the healthy growth of babies, and is also found in fermented foods and vegetables. It is a substance that works similarly to vitamins, and is present in the organs inside cells that produce energy in the human body. It is an antioxidant that has been confirmed to have the effect of suppressing multiple active oxygen species. It is said to have an antioxidant effect that suppresses cell aging, and in addition to improving cognition and memory and improving sleep, it has been found to have a positive effect on the female body. It is said to be effective in activating mitochondria and preventing cell aging.Mice raised on food that does not contain any PQQ at all have various abnormalities in their bodies due to deficiency, and it has been reported that PQQ has an important function as a nutrient. It has also been reported that in microorganisms, PQQ acts as a "coenzyme" that helps enzymes.The menstrual cycle, which is important for women, is maintained by ovulation. FSH (follicle-stimulating hormone) causes the follicle to grow, and when it grows to about 20 mm in diameter, LH (luteinizing hormone) causes the follicle to burst and ovulation occurs. One of the reasons for the decline in egg quality is an increase in active oxygen. Follicles produce energy through the action of mitochondria in the cells, and grow by utilizing that energy. Follicles are like cradles for eggs. Inside, cells called "granulosa cells" are layered, and as the follicle grows, the granulosa cells also grow. The mitochondria, the engines in the cells, produce the energy for the increase in these granulosa cells.When antioxidant power declines, active oxygen causes the follicle to fail to mature and close. PQQ has a high antioxidant effect, and is said to protect follicles from oxidative stress, encourage the maturation of follicles by allowing them to continue producing energy, and aid in ovulation.

Expected effects

① Antioxidant effect:

PQQ is a powerful antioxidant that reduces oxidative stress in the body, preventing cell aging and helping to maintain health.

② Improved egg quality:

Research suggests that PQQ has the effect of promoting follicle development and improving egg quality.

③ Improved brain function:

PQQ is said to suppress the decline of cognitive function (memory, concentration, attention, etc.) and help improve short-term memory and information processing ability. It is also expected to protect and promote the growth of nerve cells.

④ Activation of mitochondria:

Mitochondria are the energy factories of cells, and PQQ enhances mitochondrial function and promotes energy production. This is thought to lead to fatigue recovery, improved physical strength, and improved quality of life.

Summarize

PQQ functions to suppress obesity by promoting mitochondrial division and improving function, and by promoting metabolism. In other words, PQQ induces a state in the body (intracellular) that requires energy similar to muscle load, and as a result, it acts to promote catabolic metabolism. The mechanism is gradually becoming clearer regarding its effect on metabolic activators in cells related to lipid metabolism, and one of the causes is the pathway that leads to the activation of PGC-1Į via the activation of SIRT and the activation of LKB1/AMPK.