Alias: 3,3'-Dihydroxy-β,β-carotene-4,4'-dione
Origin: Haematococcus pluvialis
2. Poor water solubility and low bioavailability.
Specification: 1%-5% Astaxanthin
Advantages: Customized water solubility specifications;
High bioavailability; Good light stability; Competitive price
Appearance: Brown to red powder or crystal
Locality of growth: China
Detection method: HPLC
CAS:7542-45-2
Molecular Formula:C40H52O4
Molecular Weight:596.85g/mol
Chemical Formula:
Haematococcus pluvialis is the main source of natural astaxanthin, and its cells contain 1.5% to 3.0% astaxanthin, making it the organism with the highest natural astaxanthin content found so far. The astaxanthin contained in Haematococcus pluvialis is mainly in the trans structure (3S-3'S), which is easily absorbed by organisms.
Astaxanthin is the "strongest antioxidant" discovered by humans so far, 500 times stronger than vitamin E, and is known as the "red miracle". It has anti-aging, anti-cancer, anti-inflammatory, immune-enhancing, and photoprotective effects, and is widely used in food, medicine, agriculture and other fields. However, due to the unstable structure of natural astaxanthin, it is easily oxidized and degraded by light, and its poor water solubility is not conducive to absorption, resulting in reduced biological activity and physiological functions, thereby limiting its application. HiHealth uses its mature encapsulation technology to improve the water solubility and photothermal stability of astaxanthin.
| Specification | Water Solubility |
| 10%-20% | 50mg dissolved in 50mL water ;Reddish brown, uniform lotion50mL water |
1.Antioxidant
Astaxanthin can not only scavenge free radicals, but also quench singlet oxygen.
2.UV resistance
UVA irradiation can lead to an increase in the level of Caspase-3 protease and HO-1. After adding astaxanthin, the secretion of Caspase-3 protease and the positive regulation of HO-1 were significantly inhibited. Therefore, astaxanthin has a significant effect in protecting human epidermal fibroblasts from damage caused by UVA irradiation.
3.Reduce oxidative stress and inflammation in the body
The concentration of 8-OHdG, a DNA damage biomarker, was significantly reduced after taking astaxanthin for 4 weeks, and the plasma C-reactive protein concentration was lower than that of the control group at week 8. Therefore, dietary astaxanthin can reduce DNA damage biomarkers and acute phase proteins and enhance immune response in young healthy women.
4.Relieve eye fatigue
A double-blind randomized clinical trial recruited visual display terminal workers. The results of the study were objectively evaluated by measuring eye muscle endurance using appropriate instruments. Compared with the placebo group, the subjects who received astaxanthin had a significant reduction in eye fatigue.
5.Anti-dementia
Increased levels of Aβ(1-42) oligomers are an indicator of the development of AD, which gradually aggregates to form senile plaques. Oral administration of astaxanthin for 28 days significantly reduced the levels of Aβ(1-42) in the hippocampus of Wistar rats compared with the control group. This demonstrated the neuroprotective effect of astaxanthin against Aβ oligomers.
6.Cardiovascular disease
Astaxanthin depends on the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) signaling pathway, upregulating transcription factors Nrf2 and HO-1, thereby playing a mitochondrial protective role and delaying the occurrence and progression of heart failure.
Astaxanthin can also affect the MAPK signaling pathway by regulating the expression of c-Jun amino-terminal kinase (JNK), p38 and extracellular signal-regulated kinase, inhibit the production of inflammatory factors, and reduce the oxidative stress of myocardial cells to delay the pathological process of cardiomyopathy.
7.Regulate blood sugar and blood lipid balance
In a double blind randomized controlled trial 54 type twodiabetic patients took either 6 mg astaxanthin, 12 mg or placebo per day for 8 weeks. Astaxanthin supplementation lead to a significantdecrease in fasting blood glucose levels and HbA1c and lowered plasma IL-6 and TNF-alpha levels. The higher dose lowered plasmatriglycerides, total cholesterol and LDL levels and lowered clotting factors including plasminogen activator inhibitor and factor VII.
